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Methylprednisolone Sodium Succinate(6α-Methylprednisolone 21-hemisuccinate Sodium)
Methylprednisolone Sodium Succinate是一種糖皮質(zhì)激素,是一種具有抗炎作用的免疫抑制劑。
PF06650833
PF06650833 (PF-06650833) 是一種有效的、選擇性的和口服活性的白細(xì)胞介素 1 受體相關(guān)激酶 4 (IRAK4) 抑制劑,在細(xì)胞和 PBMC 試驗(yàn)中的 IC50 分別為 0.2 和 2.4 nM。
Arginase inhibitor 1
An arginase inhibitor
Durvalumab
Durvalumab (anti-PD-L1) is a selective, high affinity human IgG1 mAb that blocks programmed cell death ligand-1 (PD-L1) binding to PD-1 (IC50=0.1 nM) and CD80 (IC50=0.04 nM). MW=146.3 kDa.
CB-1158 (INCB01158)
Nivolumab (BMS-936558)
Nivolumab (BMS-936558) 是一種程序性死亡受體-1 (PD-1) 阻斷人 IgG4 抗體,用于治療晚期(轉(zhuǎn)移性)非小細(xì)胞肺癌。
JHU-083
JHU-083 (Ethyl 2-(2-Amino-4-methylpentanamido)-DON) is a novel prodrug of DON.JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.Solutions are best fre
C3a Receptor Agonist
A C3a receptor agonist
Furimazine (PBI 3939)
Furimazine是一種咪唑并吡嗪酮類的發(fā)光底物。在哺乳動(dòng)物細(xì)胞中,NanoLuc(Nluc)與Furimazine聯(lián)用,產(chǎn)生更亮的發(fā)光,比帶Coelenterazine的Oluc-19高250萬倍。
MCC950 (CP-456773)
An inhibitor of NLRP3 inflammasome activation
PP121
A potent dual inhibitor of tyrosine and phosphoinositide kinases
SU5416
A tyrosine kinase inhibitor
FICZ
FICZ (Formyl-indolo [3,2-b] carbazole), as an endogenous ligand for the aryl hydrocarbon receptor (AhR).
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt 是D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3) 的六鉀鹽。是一種第二信使??纱碳も}從內(nèi)質(zhì)網(wǎng)排出。
β-Zearalenol
A hepatic metabolite of zearalenone
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